NMT Medical

NMT Medical is a pioneer in the field of non-surgical repair of structural heart defects in children and adults. Over 27,000 septal defects have been closed using our proprietary technology.

Clinical Trials

Recently Completed Trials:
MIST (Migraine Intervention with STARFlex^® Technology) defined the “treatment effect” of closing a patent foramen ovale (PFO) in certain patients suffering from refractory migraine headache.

BEST (BioSTAR^® Evaluation Study) demonstrated closure rates for the worlds first bioabsorbable septal repair implant to be significantly better than competing technologies.

Ongoing Clinical trials:
CLOSURE I (enrollment completed) - compares current medical therapy to PFO closure in patients who have experienced a stroke or TIA.

MIST III - is a follow-on study to the completed MIST trial.